Researchers & Faculty
Japanese
Megumi Mizukami
Department / Course
Hokkaido University of Science Faculty of Pharmaceutical Sciences Department of Pharmacy
Job
Associate Professor
Book and thesis
Papers
Chemodivergent Reactions of Aromatic Ring-Annulated Hexahydrocyclopentafurans with Various Aldehydes Organic Letters 26 (46),pp.9909-9914 (Co-authored) 2024/11
Papers
Rational design and structure–activity relationship studies reveal new esterifed C
20
‐diterpenoid alkaloid analogues active against MCF‐7 human breast cancer cells Journal of Natural Medicines 77 (2),pp.276-283 (Co-authored) 2023/02
Papers
Discovery of C
20
-Diterpenoid Alkaloid Kobusine Derivatives Exhibiting Sub-G1 Inducing Activity ACS omega 7 (32),pp.28173-28181 (Co-authored) 2022/08
Papers
Eleven new C19-diterpenoid alkaloids from Delphinium elatum cv. Pacific Giant Journal of Natural Medicines 76 (1),pp.161-170 (Co-authored) 2022/01
Papers
New isoflavone glucosides in yabumame (Amphicarpaeabracteata (L.) Fernald subsp.edgeworthii (Benth.) H.Ohashivar.japonica (Oliv.) H.Ohashi) and their effect on leukotriene B
4
production in mast cells Journal of Natural Medicines 75 (1),pp.28-36 (Co-authored) 2021/01
Papers
Cytotoxic diterpenoid alkaloid from Aconitum japonicum subsp.subcuneatum Journal of Natural Medicines 74,pp.83-89 (Co-authored) 2020/01
Papers
Structure activity relationships and evaluation of esterified diterpenoid alkaloid derivatives as antiproliferative agents Journal of Natural Medicines (Co-authored) 2019/09
Papers
Cascade reaction including a formal [5 + 2] cycloaddition by use of alkyne-Co
2
(CO)
6
complex Tetrahedron Letters, 2019, 60 (11),pp.755-759 (Co-authored) 2019/03
Papers
Total Synthesis of Sekothrixide Strategically Utilizing Regioselective Coupling of TMS-Protected Epoxy sec-Alcohol with Gilman Reagent Journal of Organic Chemistry, 2019, 84 (3),pp.1553-1562 (Co-authored) 2019/01
Papers
Syntheses of Polycyclic Tetrahydrofurans by Cascade Reactions Consisting of Five-Membered Ring Selective Prins Cyclization and Friedel−Crafts Cyclization Journal of Organic Chemistry, 2018, 83 (16),pp.9103-9118 (Co-authored) 2018/07
Papers
Four new C19-diterpenoid alkaloids from Delphinium elatum Phytochemistry Letters, 24 (1),pp.6-9 (Co-authored) 2018/01
Papers
Synthetic study of arenicolide C: stereoselective synthesis of the C19–C36 segment Tetrahedron Letters, 2015, 56 (48),pp.6693-6695 (Co-authored) 2015/12
Papers
Total Synthesis and Structural Revision of Sekothrixide Organic Letters, 2014, 16 (11),pp.2794-2797 (Co-authored) 2014/05
Papers
Novel method for construction of tetrahydro-1-benzazepine and tetrahydro-2-benzazepine based on 7-endo selective Friedel-Crafts cyclization of vinyloxirane Tetrahedron 69 (20),pp.4120-4138 (Co-authored) 2013/05
Papers
Novel Tandem Cyclization Consisting of Five Membered-Ring Selective Prins Reaction and Subsequent Friedel-Crafts Reaction Tetrahedron Letters (Co-authored) 2012/03
Papers
Synthetic studies of the lichen macrolide lepranthin. Stereoselective synthesis of the diolide framework based on regioselective epoxide-opening reactions Chemical and Pharmaceutical Bulletin, 2011, 59 (4),pp.525-527 (Co-authored) 2011/04
Papers
Friedel-Crafts reactions of vinylaziridine linked to an ester group Heterocycles, 2011, 83 (3),pp.555-570 (Co-authored) 2011/03
Papers
Stereoselective synthesis of the C
25
-C
36
segment of arenicolides A and B: Determination of the configuration of the trisubstituted epoxide Organic Letters, 2010, 12 (5),pp.908-911 (Co-authored) 2010/03
Papers
Intramolecular Friedel-Crafts type reaction of vinyloxiranes linked to an ester group Tetrahedron, 2009, 65 (47),pp.9884-9896 (Co-authored) 2009/11
Papers
8-
Endo
selective Friedel-Crafts cyclization of vinyloxiranes with Co
2
(CO)
6
-complexed acetylene Tetrahedron Letters, 2009, 50 (1),pp.26-28 (Co-authored) 2009/01
Papers
Facile synthesis of medium-sized cyclic amines based on Friedel-Crafts reaction via iminium cation by use of acetylene dicobalt complex Tetrahedron Letters 48 (40),pp.7228-7231 (Co-authored) 2007/10
Papers
Intramolecular reaction of a phenonium ion. Novel lactonization of 4-aryl-5-tosyloxypentanoates and 4-aryl-5-tosyloxyhexanoates concomitant with a phenyl rearrangement Journal of Organic Chemistry 67 (19),pp.6618-6622 (Co-authored) 2002/09
Papers
Alkylation of 4-hydroxyproline ester derivatives. Diastereoselectivity guided by the anomeric effect and π-interaction Tetrahedron Letters 40 (16),pp.3209-3212 (Co-authored) 1999/04
