Researcher Database | Faculty of Pharmaceutical Sciences Department of Pharmacy | Koji Tsubowa |

（Last updated : 2023-09-02 22:34:58）

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Koji Tsubowa

Department / Course Hokkaido University of Science Faculty of Pharmaceutical Sciences Department of Pharmacy

Job Lecturer

Main Subject
Fundamentals for pharmacy students, Basic Chemistry, Pharmaceutical Mathematics Ⅱ, Organic Chemistry Ⅰ, Basic Pharmacy Practice Ⅰ, Clinical Pharmacy Practice Ⅲ〜Ⅴ, Comprehensive Practice Ⅱ

Academic background
2003/04/01～2008/09/25	Doctorial Graduate School of Pharmaceutical Sciences Hokkaido University Finished Doctor of Philosophy (Pharmaceutical chemistry and drug development sciences)

Research activities
2008/10/01 ～ 2010/12/31	Researcher Hokkaido University Faculty of Pharmaceutical Sciences
2011/01/01 ～ 2015/03/31	Assistant Professor Hokkaido University Faculty of Pharmaceutical Sciences
2018/04/01 ～	Lecturer Hokkaido University of Science Faculty of Pharmaceutical Sciences Department of Pharmacy

Home Page
https://researchmap.jp/takeda-k?lang=en

Present specialized field
Green sustainable chemistry, Drug development sciences, Synthetic organic chemistry keyword(Rhodium(Ⅱ) Complexes,Polymer-Supported Catalysts,Continuous Flow Synthesis,Asymmetric Catalyst,Computational Chemistry)

Belonging society
2001/02 ～	The Pharmaceutical Society of Japan
2008/04 ～	The Japanese Society for Process Chemistry
2012/11 ～	The Chemical Society of Japan
2012/11 ～	The Society of Synthetic Organic Chemistry, Japan
2021/04 ～	American Chemical Society
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Book and thesis
Books	Encyclopedia of Reagents for Organic Synthesis (Co-authored) 2014/05
Papers	Diastereo- and Enantioselective Intramolecular 1,6-C–H Insertion Reaction of Diaryldiazomethanes Catalyzed by Chiral Dirhodium(Ⅱ) Carboxylates HETEROCYCLES 103 (2),pp.1078-1098 (Co-authored) 2021/02/17
Papers	Total Synthesis of Brasilicardins A and C Organic Letters 19 (20),pp.5581-5584 (Co-authored) 2017/08/04
Papers	Diastereo- and Enantioselective Construction of 6,7-Dioxabicyclo[2.2.1]heptane Derivatives by a Dirhodium(Ⅱ)-Catalyzed Intramolecular C–H Insertion Reaction HETEROCYCLES 95 (2),pp.1211-1229 (Co-authored) 2017/02/06
Papers	Diastereo- and enantioselective intramolecular 1,6-C–H insertion reactions of α-diazo esters catalyzed by chiral dirhodium(Ⅱ) carboxylates Tetrahedron Letters 56 (11),pp.1397-1400 (Co-authored) 2015/03/11
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Academic conference presentation
2023/07/19	Crosslinking Polymer-Supported Rh(II) Complex: Soluble and Reusable Catalyst for Asymmetric Intramolecular C-H Insertion Reactions (The 13th SPSJ International Polymer Conference)
2023/03/27	Dirhodium(II) complex-catalyzed enantioselective carbonyl ylide cycloaddition reactions under continuous flow conditions (ACS Spring 2023)
2023/01/23	Development of soluble cross-linked polymer-supported Rh(II) complexes usable at low temperatures (The 57th Hokkaido Section Research and Presentation Meeting)
2022/09/07	Continuous Flow System with a Polymer-Supported Dirhodium(II) Complex: Application to Enantioselective Carbonyl Ylide Cycloaddition Reactions
2022/08/24	Immobilization of mixed-ligand chiral rhodium(Ⅱ) complex for asymmetric intramolecular C–H Insertion reactions (ACS Fall 2022)
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Lecturer and lecture
2013/12/04	Insoluble Polymer-Supported Dirhodium(Ⅱ) Catalysts for Asymmetric Reactions (Hokkaido)

Winning science prize
2011/11	Thieme Synfacts of the month (A Flow System for Enantioselective Carbonyl Ylide Cycloaddition)
2010/12	The American Chemical Scoety Best poster award in Pacifichem 2010
2010/12	Thieme Synfacts of the month (Synthesis of endo-6-Aryl-8-oxabicyclo-[3.2.1]oct-3-en-2-one)
2007/08	Elsevier B.V. Tetrahedron Most Cited Paper 2004-2007 Award Elsevier

Research topic, funded research, and department laboratory expense
2021/04 ～ 2025/03	Immobilization of Mixed-Ligand Chiral Rhodium(II) Complex into Soluble Polymer–Supports Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C) keyword(Polymer-Supported Catalysts, Rhodium(Ⅱ) Complexes)
2014/04 ～ 2016/03	Enantio- and Diastereoselective Cyclopropanation with Halodiazoacetophenone Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B) keyword(Organic Synthesis, Asymmetric Catalyst, Rhodium(Ⅱ) Complexes)
2012/04 ～ 2014/03	Polymer-Supported Chiral Dirhodium(Ⅱ) Complex for Asymmetric Reactions Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (B) keyword(Enantioselective Catalytic Reaction, Dirhodium (Ⅱ) Complex, Heterogeneous Catalysts)

Acquisition patent
2008/01/31	POLYMER-SUPPORTED METAL COMPLEX CATALYST （WO/2008/013009）