Researchers & Faculty
Japanese
Ryosuke Tatsunami
Department / Course
Hokkaido University of Science Faculty of Pharmaceutical Sciences Department of Pharmacy
Job
Professor
Book and thesis
Papers
Epalrestat enhances MTS reduction activity independent of cell numbers in bovine aortic endothelial cells Pharmacology & Pharmacy 14 (3) (Co-authored) 2023/03
Papers
Effect of Chloroquine on Doxorubicin-induced Apoptosis in A549 Cells Anticancer Res. 42 (8),pp.4025-4035 (Co-authored) 2022/08
Papers
Involvement of Circadian Clock Gene BMAL1 in Doxorubicin-Induced Inflammation in Vascular Smooth Muscle Cells Pharmacology & Pharmacy 42 (8),pp.4025-4035 (Co-authored) 2021/11
Papers
Epalrestat suppresses inflammatory response in LPS-stimulated RAW264.7 cells Allergol Immunopathol (Madr) 49 (5),pp.1-8 (Co-authored) 2021/09
Papers
Effects of Kumaizasa (Sasa senanensis) Leaf Extract on Innate Immune Regulation in HEK293 Cells and Macrophages Anticancer Res. 41 (8),pp.4093-4100 (Co-authored) 2021/08
Papers
Epalrestat suppresses cadmium-induced cytotoxicity through Nrf2 in endothelial cells Exp. Ther. Med. 21 (4),pp.393 (Co-authored) 2021/02
Papers
Protective Effect of Epalrestat against Oxidative Stress-induced Cytotoxicity,pp.1381-1388 (Co-authored) 2020/11
Papers
Autophagy activation is required for homocysteine-induced apoptosis in bovine aorta endothelial cells Heliyon 6 (1),pp.e03315 (Co-authored) 2020/01
Papers
ROS-induced ROS release orchestrated by Nox4, Nox2, and mitochondria in VEGF signaling and angiogenesis AJP Cell Physiology 312 (6),pp.C748-C764 (Co-authored) 2017/04
Papers
Long-term treatment of clarithromycin at a low concentration improves hydrogen peroxide-induced oxidant/antioxidant imbalance in human small airway epithelial cells by increasing Nrf2 mRNA expression BMC Pharmacol. Toxicol. 18 (1),pp.15 (Co-authored) 2017/02
Papers
Epalrestat Upregulates Heme Oxygenase-1, Superoxide Dismutase, and Catalase in Cells of the Nervous System Biol. Pharm. Bull. 39,pp.1523-1530 (Co-authored) 2016/07
Papers
Glycolaldehyde induces endoplasmic reticulum stress and apoptosis in Schwann cells Toxicol. Rep. 2,pp.1454-1462 (Co-authored) 2015/11
Papers
Epalrestat increases glutathione, thioredoxin, and heme oxygenase-1 by stimulating Nrf2 pathway in endothelial cells Redox Biology 4,pp.87-96 (Co-authored) 2015/04
Papers
Epalrestat increases intracellular glutathione levels in Schwann cells through transcription regulation transcription regulation Redox Biol. 2,pp.15-21 (Co-authored) 2014/01
Papers
Glycolaldehyde induces cytotoxicity and increases glutathione and multidrug-resistance-associated protein levels in Schwann cells Biol. Pharm. Bull. 36 (7),pp.1111-1117 (Co-authored) 2013/07
Papers
Methylglyoxal has deleterious effects on thioredoxin in human aortic endothelial cells Environ. Toxicol. Pharmacol. 34 (2),pp.117-126 (Co-authored) 2012/09
Papers
Multidrug resistance associated protein 1 together with glutathione plays a protective role against 4-hydroxy-2-nonenal-induced oxidative stress in bovine aortic endothelial cells Biol. Pharm. Bull. 35 (8),pp.1269-1274 (Co-authored) 2012/08
Papers
Buthionine sulfoximine promotes methylglyoxal-induced apoptotic cell death and oxidative stress in endothelial cells Biological and Pharmaceutical Bulletin (Co-authored) 2010/04
Papers
Methylglyoxal causes dysfunction of thioredoxin and thioredoxin reductase in endothelial cells J. Pharmacol. Sci. 111 (4),pp.426-432 (Co-authored) 2009/12
Papers
Multidrug-resistance-associated protein plays a protective role in menadione-induced oxidative stress in endothelial cells Life Sci. 84 (7-8.),pp.211-217 (Co-authored) 2009/02
Papers
Methylglyoxal-induced superoxide anion production in endothelial cells,pp.147-153 (Co-authored) 2009/01
Papers
Methylglyoxal-inducedapoptosis of endothelial cells,pp.1443-1448 (Co-authored) 2008/10
Papers
Enzymatic and mechanistic studies on the form N-phenylglycolohydroxamication of acid from nitrosobenzene and pyruvate in spinach leaf homogenate J. Agric. Food Chem. 54 (2),pp.590-596 (Co-authored) 2006/01
Papers
Structure-activity relationships in the deacetylation of O-glucosides of N-hydroxy-N-arylacylamides by mammalian liver microsomes Chem. Biol. Interact. 137 (1),pp.25-42 (Co-authored) 2001/07
Papers
Structure Determination of Methyl Nicotinate and Methyl Picolinate by Gas Electron Diffraction Combined with ab Initio Calculations The Journal of Physical Chemistry A (Co-authored) 1998/01