大谷　紘資｜薬学部薬学科｜教員紹介｜北海道科学大学研究者データベース

オオタニ　コウスケ Kosuke Otani
大谷　紘資

所属北海道科学大学薬学部薬学科

職種講師

著書・論文歴
著書	愛玩動物看護師必携テキスト (共著) 2022/12/21
論文	A selective eukaryotic elongation factor 2 kinase inhibitor, A484954 lowered blood glucose in Zucker fatty diabetes mellitus rat. Journal of pharmacological sciences 158 (3),270-275 (共著) 2025/07
論文	Senescent cardiac fibroblasts-derived extracellular vesicles induced autophagy in cardiac fibroblasts via suppression of ras homolog enriched in brain like 1. Journal of pharmacological sciences 158 (1),1-7 (共著) 2025/05
論文	Development of an Effective Isolation Method for Plasma Extracellular Vesicles Excluding Lipoproteins by Precipitation With Polyethylene Glycol. Journal of extracellular biology 4 (4),e70047 (共著) 2025/04
論文	The eukaryotic elongation factor 2 kinase inhibitor, A484954, induces hypoglycaemic and hypotensive effects. British journal of pharmacology 182 (8),1823-1835 (共著) 2025/04
論文	Minocycline prevents monocrotaline-induced pulmonary hypertension through the attenuation of endothelial dysfunction and vascular wall thickening. Journal of pharmacological sciences 157 (1),39-44 (共著) 2025/01
論文	Protective function of the voltage-gated potassium channel Kv11.3 in a mouse model of cardiac ischemia/reperfusion injury. PloS one 20 (5),e0323428 (共著) 2025
論文	Alteration of reactivity in isolated mesenteric artery from Zucker fatty diabetes mellitus rats. Journal of pharmacological sciences 156 (1),38-44 (共著) 2024/09
論文	Human omentin-1 reduces vascular insulin resistance and hypertension in Otsuka Long-Evans Tokushima Fatty rats. Naunyn-Schmiedeberg's archives of pharmacology 397 (5),3379-3387 (共著) 2024/05
論文	Eukaryotic elongation factor 2 kinase inhibitor, A484954 induced diuresis via nitric oxide production in spontaneously hypertensive rats. The Journal of veterinary medical science 85 (12),1314-1318 (共著) 2023/12
論文	Autocrine role of senescent cardiac fibroblasts-derived extracellular vesicles. The Journal of veterinary medical science 85 (11),1157-1164 (共著) 2023/11
論文	Human Omentin-1 Administration Ameliorates Hypertensive Complications without Affecting Hypertension in Spontaneously Hypertensive Rats. International journal of molecular sciences 24 (4) (共著) 2023/02
論文	Chemerin fragments show different effects on systemic blood pressure dependent on carboxyl-terminal cleavage site. The Journal of veterinary medical science 84 (10),1352-1357 (共著) 2022/09
論文	Eukaryotic elongation factor 2 kinase inhibitor, A484954 inhibits perivascular sympathetic nerve stimulation-induced vasoconstriction in isolated renal artery. European journal of pharmacology 926,175042 (共著) 2022/07
論文	Cardiovascular Characteristics of Zucker Fatty Diabetes Mellitus Rats, an Animal Model for Obesity and Type 2 Diabetes. International journal of molecular sciences 23 (8) (共著) 2022/04
論文	Chemerin-9 stimulates migration in rat cardiac fibroblasts in vitro. European journal of pharmacology 912,174566 (共著) 2021/12
論文	Eukaryotic elongation factor 2 kinase inhibitor, A484954 induces diuretic effect via renal vasorelaxation in spontaneously hypertensive rats. European journal of pharmacology 913,174637 (共著) 2021/12
論文	Chemokine-like Receptor 1 in Brain of Spontaneously Hypertensive Rats Mediates Systemic Hypertension. International journal of molecular sciences 22 (21) (共著) 2021/10
論文	A single injection of periostin decreases cardiac voltage-gated Na+ channel in rat ventricles. The Journal of veterinary medical science 83 (6),997-1003 (共著) 2021/07
論文	Age-dependent increase in activity of eukaryotic elongation factor 2 kinase in mesenteric arteries from spontaneously hypertensive rats. The Journal of veterinary medical science 83 (1),42-47 (共著) 2021/01
論文	Preventive Effect of Canstatin against Ventricular Arrhythmia Induced by Ischemia/Reperfusion Injury: A Pilot Study. International journal of molecular sciences 22 (3) (共著) 2021/01
論文	Ⅳ型コラーゲン分解産物の臨床応用に向けた基礎研究の展開日本薬理学雑誌 156 (5),282-287 (共著) 2021
論文	Decreased Expression of Canstatin in Rat Model of Monocrotaline-Induced Pulmonary Arterial Hypertension: Protective Effect of Canstatin on Right Ventricular Remodeling. International journal of molecular sciences 21 (18) (共著) 2020/09
論文	Plasma small extracellular vesicles in hypertensive rats impair reactivity of isolated blood vessels. The Journal of veterinary medical science 82 (7),897-902 (共著) 2020/07
論文	Chemerin-9-induced contraction was enhanced through the upregulation of smooth muscle chemokine-like receptor 1 in isolated pulmonary artery of pulmonary arterial hypertensive rats. Pflugers Archiv : European journal of physiology 472 (3),335-342 (共著) 2020/03
論文	Small extracellular vesicles from rat plasma promote migration and proliferation of vascular smooth muscle cells. The Journal of veterinary medical science 82 (3),299-306 (共著) 2020/03
論文	Optimal Isolation Method of Small Extracellular Vesicles from Rat Plasma. International journal of molecular sciences 20 (19) (共著) 2019/09
論文	Plasma exosomes regulate systemic blood pressure in rats. Biochemical and biophysical research communications 503 (2),776-783 (共著) 2018/09
論文	Diverse distribution of tyrosine receptor kinase B isoforms in rat multiple tissues. The Journal of veterinary medical science 79 (9),1516-1523 (共著) 2017/09
論文	Vasculo-protective effect of BMS-309403 is independent of its specific inhibition of fatty acid-binding protein 4. Pflugers Archiv : European journal of physiology 469 (9),1177-1188 (共著) 2017/09
論文	Expression pattern and function of tyrosine receptor kinase B isoforms in rat mesenteric arterial smooth muscle cells. Biochemical and biophysical research communications 467 (4),683-9 (共著) 2015/11
論文	Death-associated protein kinase 3 mediates vascular structural remodelling via stimulating smooth muscle cell proliferation and migration. Clinical science (London, England : 1979) 127 (8),539-48 (共著) 2014/10