水上　徳美｜薬学部薬学科｜教員紹介｜北海道科学大学研究者データベース

ミズカミ　メグミ Megumi Mizukami
水上　徳美

所属北海道科学大学薬学部薬学科

職種准教授

著書・論文歴
著書	「著書」症例まるごと基礎から解析　臨床薬学総論　患者ケアへのアプローチ　第２版 (共著) 2010/04
論文	Chemodivergent Reactions of Aromatic Ring-Annulated Hexahydrocyclopentafurans with Various Aldehydes Organic Letters 26 (46),9909-9914頁 (共著) 2024/11
論文	Rational design and structure–activity relationship studies reveal new esterifed C₂₀‐diterpenoid alkaloid analogues active against MCF‐7 human breast cancer cells Journal of Natural Medicines 77 (2),276-283頁 (共著) 2023/02
論文	Discovery of C₂₀-Diterpenoid Alkaloid Kobusine Derivatives Exhibiting Sub-G1 Inducing Activity ACS omega 7 (32),28173-28181頁 (共著) 2022/08
論文	Eleven new C19-diterpenoid alkaloids from Delphinium elatum cv. Pacific Giant Journal of Natural Medicines 76 (1),161-170頁 (共著) 2022/01
論文	New isoflavone glucosides in yabumame (Amphicarpaeabracteata (L.) Fernald subsp.edgeworthii (Benth.) H.Ohashivar.japonica (Oliv.) H.Ohashi) and their effect on leukotriene B₄ production in mast cells Journal of Natural Medicines 75 (1),28-36頁 (共著) 2021/01
論文	Cytotoxic diterpenoid alkaloid from Aconitum japonicum subsp.subcuneatum Journal of Natural Medicines 74,83-89頁 (共著) 2020/01
論文	Structure activity relationships and evaluation of esterified diterpenoid alkaloid derivatives as antiproliferative agents Journal of Natural Medicines (共著) 2019/09
論文	Cascade reaction including a formal [5 + 2] cycloaddition by use of alkyne-Co₂(CO)₆ complex Tetrahedron Letters, 2019, 60 (11),755-759頁 (共著) 2019/03
論文	Total Synthesis of Sekothrixide Strategically Utilizing Regioselective Coupling of TMS-Protected Epoxy sec-Alcohol with Gilman Reagent Journal of Organic Chemistry, 2019, 84 (3),1553-1562頁 (共著) 2019/01
論文	Syntheses of Polycyclic Tetrahydrofurans by Cascade Reactions Consisting of Five-Membered Ring Selective Prins Cyclization and Friedel−Crafts Cyclization Journal of Organic Chemistry, 2018, 83 (16),9103-9118頁 (共著) 2018/07
論文	Four new C19-diterpenoid alkaloids from Delphinium elatum Phytochemistry Letters, 24 (1),6-9頁 (共著) 2018/01
論文	スピロ型アレーニウムイオンを経由する環化反応および骨格変換反応有機合成化学協会誌, 2016, 74 (1),18-30頁 (共著) 2016/01
論文	Synthetic study of arenicolide C: stereoselective synthesis of the C19–C36 segment Tetrahedron Letters, 2015, 56 (48),6693-6695頁 (共著) 2015/12
論文	Total Synthesis and Structural Revision of Sekothrixide Organic Letters, 2014, 16 (11),2794-2797頁 (共著) 2014/05
論文	Novel method for construction of tetrahydro-1-benzazepine and tetrahydro-2-benzazepine based on 7-endo selective Friedel-Crafts cyclization of vinyloxirane Tetrahedron 69 (20),4120-4138頁 (共著) 2013/05
論文	Novel Tandem Cyclization Consisting of Five Membered-Ring Selective Prins Reaction and Subsequent Friedel-Crafts Reaction Tetrahedron Letters (共著) 2012/03
論文	Tandem five membered-ring selective Prins reaction and Friedel-Crafts reaction Tetrahedron Letters, 2012, 53 (11),1337-1340頁 (共著) 2012/03
論文	Synthetic studies of Venturicidins:stereoselective synthesis of the C15-C27 segment based on two types of stereospecific epoxide opening reactions Tetrahedron Letters, 2011, 52 (51),6948-6951頁 (共著) 2011/12
論文	Synthetic studies of the lichen macrolide lepranthin. Stereoselective synthesis of the diolide framework based on regioselective epoxide-opening reactions Chemical and Pharmaceutical Bulletin, 2011, 59 (4),525-527頁 (共著) 2011/04
論文	Friedel-Crafts reactions of vinylaziridine linked to an ester group Heterocycles, 2011, 83 (3),555-570頁 (共著) 2011/03
論文	Synthetic studies of lepranthin, a lichen-produced dimeric macrolide. Stereoselective synthesis of a seco-acid based on stereospecific epoxide-opening reactions Heterocycles, 2011, 83 (2),293-298頁 (共著) 2011/02
論文	Stereoselective synthesis of the C₂₅-C₃₆ segment of arenicolides A and B: Determination of the configuration of the trisubstituted epoxide Organic Letters, 2010, 12 (5),908-911頁 (共著) 2010/03
論文	Intramolecular Friedel-Crafts type reaction of vinyloxiranes linked to an ester group Tetrahedron, 2009, 65 (47),9884-9896頁 (共著) 2009/11
論文	8-Endo selective Friedel-Crafts cyclization of vinyloxiranes with Co₂(CO)₆-complexed acetylene Tetrahedron Letters, 2009, 50 (1),26-28頁 (共著) 2009/01
論文	含窒素環状化合物の新規構築法の開発および立体選択的アルキル化反応に関する研究（博士論文） (単著) 2008/03
論文	Novel construction of hydro-2-benzazepines based on 7-endo selective Friedel-Crafts-type reaction of vinyloxiranes Tetrahedron Letters, 2007, 48 (48),8558-8561頁 (共著) 2007/11
論文	Facile synthesis of medium-sized cyclic amines based on Friedel-Crafts reaction via iminium cation by use of acetylene dicobalt complex Tetrahedron Letters 48 (40),7228-7231頁 (共著) 2007/10
論文	Intramolecular reaction of a phenonium ion. Novel lactonization of 4-aryl-5-tosyloxypentanoates and 4-aryl-5-tosyloxyhexanoates concomitant with a phenyl rearrangement Journal of Organic Chemistry 67 (19),6618-6622頁 (共著) 2002/09
論文	Alkylation of 4-hydroxyproline ester derivatives. Diastereoselectivity guided by the anomeric effect and π-interaction Tetrahedron Letters 40 (16),3209-3212頁 (共著) 1999/04